
If you're looking for a SUV with versatility, style, and power that you will be proud to drive, you're likely looking at Acura models and their competitors. In this luxury crossover comparison, we’re dissecting the specs of SUVs from Acura and Lexus to help you make a decision on which vehicle you want to sit in your driveway. Keep reading to learn more about the Acura MDX vs Lexus RX 350, then visit Greensboro Acura to test-drive the MDX today.
Power and Performance

Pop the hood of the MDX and feast your eyes on the 3.5-liter V6 engine, which is capable of delivering 290 horsepower and 267 pound-feet of torque. With a 10-speed automatic transmission, your SUV will shift gears seamlessly, whether you’re embarking on a cross-country road trip or driving home from the grocery store. Look for an Acura MDX for sale near you at our Greensboro Acura dealership if you enjoy recreational activities, such as camping and boating. Its towing capacity is 5,000 pounds, so you can hitch your trailer or boat with ease.*
With a 2.4-liter turbocharged engine, the Lexus RX 350 can crank out 275 horsepower and 317 pound-feet of torque. Unlike the MDX, the Lexus crossover has an 8-speed automatic transmission, and its towing capacity caps at 3,500 pounds with additional equipment.^ Both the Lexus RX 350 and the Acura MDX are available with either front-wheel drive or all-wheel drive.
Interior Design

The Acura MDX has enough room for seven passengers to sit comfortably on three rows of seats. When you fold down the second and third rows, you will have access to a whopping 95 cubic feet of maximum cargo space, perfect for stashing bulky belongings. If you often travel with a large family or transport lots of equipment for work, you may prefer the MDX for its space and style.
The interior of the RX 350 is smaller, offering two rows of seats for a total of five passengers. This SUV has an standard leather-trimmed steering wheel and heated front seats, like its Acura counterpart. It also provides 46.2 cubic feet of cargo volume with the rear seats folded. The RX 350 may be ideal for drivers who travel in smaller groups but still like plenty of room for bringing their items with them.
Exterior Design
Whether you stop at a traffic light in the MDX or the RX 350, drivers and pedestrians will admire the stylish exterior design of your SUV. Both vehicles heighten your visibility on the road with LED headlights and taillights, daytime running lights, and fog lights. The side mirrors on both vehicles are also heated, clearing up fog from your view as you drive in the early hours of the morning.
In the MDX, the panoramic moonroof is controllable with a remote, and it tilts and slides to let in fresh air. On higher trim levels, such as the Advance, A-Spec®, and Type S Advance, the power liftgate with hands-free access is a standard feature, so you can open your trunk by kicking your leg under the vehicle while your hands are full. The Acura MDX Type S Advance also boasts 21-inch Berlina black wheels.
Roof rails are available on all configurations of the RX 350 and the Acura MDX. You can also hit the road with 21-inch, 20-spoke wheels with a metallic finish if you invest in top trim levels of the Lexus crossover.
Safety and Technology

The luxurious interior of both SUVs are also equipped with advanced technology to keep you and your passengers safe and entertained. The Acura MDX safety features help you navigate congested highways with traffic jam assist, a standard feature that centers your vehicle in the lane and stops and accelerates on your behalf. On higher trim levels, you can monitor the area you’re in with the surround view camera. This SUV may appeal to you if you want to host an epic concert by blasting music in the available 19-speaker Bang & Olufsen sound system. Higher trims also grant you access to more tech features, such as a head-up display and third-row USB charging ports.
What makes the RX 350 stand out is its optional Advanced Park function, which guides you to steer your vehicle into a tight space. The available 14-inch touchscreen is also larger than the display in the Acura, ideal as you look for directions to your destination or see the next song on your music playlist.
Explore the Acura MDX at Greensboro Acura
The 2025 Acura MDX specs offer the perfect blend of power, style, and safety that you’re looking for in your new ride. If you are in the market for a new Acura MDX or even a quality used Acura, stop by our Acura dealership in Greensboro to take the luxury SUV out for a spin or inquire about a used Acura MDX for sale near you.[DISCLAIMERS]
*5,000 lb. capacity is with the optional Acura Genuine Accessory ATF cooler. Towing requires the addition of the Acura accessory trailer hitch and hitch ball. Please see your Acura dealer for details. Number of occupants and added cargo weight in the vehicle may reduce max towing capacity, see Owner's Guide for details.
^Never tow beyond a vehicle's published towing capacities.